Ausgewählte Publikationen

BDNF: mRNA expression in urine cells of patients with chronic kidney disease and its role in kidney function.

Endlich N, Lange T, Kuhn J, Klemm P, Kotb AM, Siegerist F, Kindt F, Lindenmeyer MT, Cohen CD, Kuss AW, Nath N, Rettig R, Lendeckel U, Zimmermann U, Amann K, Stracke S, Endlich K.

J Cell Mol Med. 2018 Aug 21. doi: 10.1111/jcmm.13762. [Epub ahead of print]

  

Novel Microscopic Techniques for Podocyte Research.

Siegerist F, Endlich K, Endlich N.

Front Endocrinol (Lausanne). 2018 Jul 11;9:379. eCollection 2018. Review.

 

The Role of Palladin in Podocytes.

Artelt N, Ludwig TA, Rogge H, Kavvadas P, Siegerist F, Blumenthal A, van den Brandt J, Otey CA, Bang ML, Amann K, Chadjichristos CE, Chatziantoniou C, Endlich K, Endlich N.

J Am Soc Nephrol. 2018 Jun;29(6):1662-1678.

 

The transcription factor Dach1 is essential for podocyte function.

Endlich N, Kliewe F, Kindt F, Schmidt K, Kotb AM, Artelt N, Lindenmeyer MT, Cohen CD, Döring F, Kuss AW, Amann K, Moeller MJ, Kabgani N, Blumenthal A, Endlich K.

J Cell Mol Med. 2018 May;22(5):2656-2669.

 

Structured illumination microscopy and automatized image processing as a rapid diagnostic tool for podocyte effacement.

Siegerist F, Ribback S, Dombrowski F, Amann K, Zimmermann U, Endlich K, Endlich N.

Sci Rep. 2017 Sep 13;7(1):11473.

 

Identification of miR-16 as an endogenous reference gene for the normalization of urinary exosomal miRNA expression data from CKD patients.

Lange T, Stracke S, Rettig R, Lendeckel U, Kuhn J, Schlüter R, Rippe V, Endlich K, Endlich N.

PLoS One. 2017 Aug 31;12(8):e0183435.

 

Studying the role of fascin-1 in mechanically stressed podocytes.

Kliewe F, Scharf C, Rogge H, Darm K, Lindenmeyer MT, Amann K, Cohen CD, Endlich K, Endlich N.

Sci Rep. 2017 Aug 30;7(1):9916.

 

Automated segmentation and quantification of actin stress fibres undergoing experimentally induced changes.

Rogge H, Artelt N, Endlich N, Endlich K.

J Microsc. 2017 Nov;268(2):129-140.

 

Acute podocyte injury is not a stimulus for podocytes to migrate along the glomerular basement membrane in zebrafish larvae.

Siegerist F, Blumenthal A, Zhou W, Endlich K, Endlich N.

Sci Rep. 2017 Mar 2;7:43655. 

 

A novel assay to assess the effect of pharmaceutical compounds on the differentiation of podocytes.

Kindt F, Hammer E, Kemnitz S, Blumenthal A, Klemm P, Schlüter R, Quaggin SE, van den Brandt J, Fuellen G, Völker U, Endlich K, Endlich N.

Br J Pharmacol. 2017 Jan;174(2):163-176. 

 

4D in vivo model imaging of glomerular barrier function in a zebrafish podocyte injury model.

Siegerist F, Zhou W, Endlich K, Endlich N.

Acta Physiol (Oxf). 2016 Jul 14. doi: 10.1111/apha.12754. [Epub ahead of print].

 

Knockdown of ApoL1 in Zebrafish Larvae Affects the Glomerular Filtration Barrier and the Expression of Nephrin.

Kotb AM, Simon O, Blumenthal A, Vogelgesang S, Dombrowski F, Amann K, Zimmermann U, Endlich K, Endlich N.

PLoS One. 2016 May 3;11(5).

 

Mechanical stress enhances CD9 expression in cultured podocytes.

Blumenthal A, Giebel J, Warsow, G, Li L, Ummanni R, Schordan S, Schordan E, Klemm P, Gretz N, Endlich K, Endlich N.

Am J Physiol Renal Physiol. 2015 Mar 15;308(6):F602-13. 

 

Cohort profile: Greifswald approach to individualized medicine (GANI_MED).

Grabe HJ, Assel H, Bahls T, Dörr M, Endlich K, Endlich N, ...., Werner V, Zygmunt MT, Kroemer HK. (55 authors)

J Transl Med. 2014 May 23;12:144.

 

Two-Photon Microscopy Reveals Stationary Podocytes in Living Zebrafish Larvae.

Endlich N, Simon O, Göpferich A, Wegner H, Moeller MJ, Rumpel E, Kotb AM, Endlich K.

J Am Soc Nephrol. 2014 (Apr;25(4):681-6.

 

OPN deficiency results in severe glomerulosclerosis in uninephrectomized mice.

Schordan S, Grisk O, Schordan E, Miehe B, Rumpel E, Endlich K, Giebel J, Endlich N.

Am J Physiol Renal Physiol. 2013 Jun 15;304(12):F1458-70.

 

PodNet, a protein-protein interaction network of the podocyte.

Warsow G, Endlich N, Schordan E, Schordan S, Chilukoti RK, Homuth G, Moeller MJ, Fuellen G, Endlich K.

Kidney Int. 2013 Jul;84(1):104-15.

 

The challenge and response of podocytes to glomerular hypertension.

Endlich N, Endlich K.

Semin Nephrol. 2012 Jul;32(4):327-41.

 

Morphology and migration of podocytes are affected by CD151 levels.

Blumenthal A, Giebel J, Ummanni R, Schlüter R, Endlich K, Endlich N.

Am J Physiol Renal Physiol. 2012 May 15;302(10):F1265-77.

 

Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function.

Chasman DI, Fuchsberger C, Pattaro C, Teumer A, Böger CA, Endlich K, .... Kao WH, Fox CS, Köttgen A. (164 authors and 4 consortia)

Hum Mol Genet. 2012 Dec 15;21(24):5329-43.

 

Primary cultures of glomerular parietal epithelial cells or podocytes with proven origin.

Kabgani N, Grigoleit T, Schulte K, Sechi A, Sauer-Lehnen S, Tag C, Boor P, Kuppe C, Warsow G, Schordan S, Mostertz J, Chilukoti RK, Homuth G, Endlich N, Tacke F, Weiskirchen R, Fuellen G, Endlich K, Floege J, Smeets B, Moeller MJ.

PLoS One. 2012;7(4):e34907.

 

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis.

Bollée G, Flamant M, Schordan S, Fligny C, Rumpel E, Milon M, Schordan E, Sabaa N, Vandermeersch S, Galaup A, Rodenas A, Casal I, Sunnarborg SW, Salant DJ, Kopp JB, Threadgill DW, Quaggin SE, Dussaule JC, Germain S, Mesnard L, Endlich K, Boucheix C, Belenfant X, Callard P, Endlich N, Tharaux PL.

Nat Med. 2011 Sep 25;17(10):1242-50. Erratum in: Nat Med. 2011 Oct;17(10):2 p following 1250. Nat Med. 2011 Nov;17(11):1521.

 

Non-muscle myosin IIA is required for the development of the zebrafish glomerulus.

Müller T, Rumpel E, Hradetzky S, Bollig F, Wegner H, Blumenthal A, Greinacher A, Endlich K, Endlich N.

Kidney Int. 2011 Nov;80(10):1055-63.

 

AlphaV-integrins mediate the mechanoprotective action of osteopontin in podocytes.

Schordan S, Schordan E, Endlich K, Endlich N.

Am J Physiol Renal Physiol. 2011 Jan;300(1):F119-32.

 

ExprEssence--revealing the essence of differential experimental data in the context of an interaction/regulation net-work.

Warsow G, Greber B, Falk SS, Harder C, Siatkowski M, Schordan S, Som A, Endlich N, Schöler H, Repsilber D, Endlich K, Fuellen G.

BMC Syst Biol. 2010 Nov 30;4:164.

 

New loci associated with kidney function and chronic kidney disease.

Köttgen A, Pattaro C, Böger CA, .....Endlich K, Völzke H, Kroemer HK, ....., Rettig R, Hastie N, Chasman DI, Kao WH, Heid IM, Fox CS. (131 authors).

Nat Genet. 2010 May;42(5):376-84.

 

Alterations of the podocyte proteome in response to high glucose concentrations.

Schordan S, Schordan E, Endlich N, Lindenmeyer MT, Meyer-Schwesinger C, Meyer TN, Giebel J, Cohen CD, Endlich K, Maurer MH.

Proteomics. 2009 Oct;9(19):4519-28

 

Palladin is a dynamic actin-associated protein in podocytes.

Endlich N, Schordan E, Cohen CD, Kretzler M, Lewko B, Welsch T, Kriz W, Otey CA, Endlich K; European Renal cDNA Bank Consortium.

Kidney Int. 2009 Jan;75(2):214-26

 

Movement of stress fibers away from focal adhesions identifies focal adhesions as sites of stress fiber assembly in stationary cells.

Endlich N, Otey CA, Kriz W, Endlich K.

Cell Motil Cytoskeleton. 2007 Dec;64(12):966-76

 

Podocytes are sensitive to fluid shear stress in vitro.

Friedrich C, Endlich N, Kriz W, Endlich K.

Am J Physiol Renal Physiol. 2006 Oct;291(4):F856-65. 

 

Stretch, tension and adhesion - adaptive mechanisms of the actin cytoskeleton in podocytes.

Endlich N, Endlich K.

Eur J Cell Biol. 2006 Apr;85(3-4):229-34

 

Association of CD2AP with dynamic actin on vesicles in podocytes.

Welsch T, Endlich N, Gökce G, Doroshenko E, Simpson JC, Kriz W, Shaw AS, Endlich K.

Am J Physiol Renal Physiol. 2005 Nov;289(5):F1134-43

 

Stable expression of nephrin and localization to cell-cell contacts in novel murine podocyte cell lines.

Schiwek D, Endlich N, Holzman L, Holthöfer H, Kriz W, Endlich K.

Kidney Int. 2004 Jul;66(1):91-101

 

Analysis of differential gene expression in stretched podocytes: osteopontin enhances adaptation of podocytes to mechanical stress.

Endlich N, Sunohara M, Nietfeld W, Wolski EW, Schiwek D, Kränzlin B, Gretz N, Kriz W, Eickhoff H, Endlich K.

FASEB J. 2002 Nov;16(13):1850-2

 

Podocytes respond to mechanical stress in vitro.

Endlich N, Kress KR, Reiser J, Uttenweiler D, Kriz W, Mundel P, Endlich K.

J Am Soc Nephrol. 2001 Mar;12(3):413-22