AG Völker

Publikationen 2004-2011

  • Bien, S.; Ritter, C. A.; Kranz, M.; Scharf, C.; Steil, L.; Hummel, M.; Völker, U.; Cascorbi, I. and Kroemer, H. K.: Influence of doxorubicin on gene expression and protein pattern in HeLa cells. Int J Clin Pharmacol Ther 42, 640-641 (2004).
  • Costa, T.; Steil, L.; Martins, L. O.; Völker, U. and Henriques, A. O.: Assembly of an oxalate decarboxylase produced under sigmaK control into the Bacillus subtilis spore coat. J. Bacteriol. 186, 1462-1474 (2004).
  • Delumeau, O.; Dutta, S.; Brigulla, M.; Kuhnke, G.; Hardwick, S. W.; Völker, U.; Yudkin, M. D. and Lewis, R. J.: Functional and structural characterization of RsbU, a stress signaling protein phosphatase 2C. J. Biol. Chem. 279, 40927-40937 (2004).
  • Eymann, C.; Dreisbach, A.; Albrecht, D.; Bernhardt, J.; Becher, D.; Gentner, S.; Tam le, T.; Büttner, K.; Buurman, G.; Scharf, C.; Venz, S.; Völker, U. and Hecker, M.: A comprehensive proteome map of growing Bacillus subtilis cells. Proteomics 4, 2849-2876 (2004).
  • Hecker, M. and Völker, U.: Towards a comprehensive understanding of Bacillus subtilis cell physiology by physiological proteomics. Proteomics 4, 3727-3750 (2004).
  • Holtmann, G.; Brigulla, M.; Steil, L.; Schütz, A.; Barnekow, K.; Völker, U. and Bremer, E.: RsbV-independent induction of the SigB-dependent general stress regulon of Bacillus subtilis during growth at high temperature. J Bacteriol. 186, 6150-6158 (2004).
  • Laukel, M.; Rossignol, M.; Borderies, G.; Völker, U. and Vorholt, J. A.: Comparison of the proteome of Methylobacterium extorquens AM1 grown under methylotrophic and non-methylotrophic growth conditions. Proteomics 4, 1247-1264 (2004).
  • Walther, R.; Balabanov, S.; Junker, H.; Scharf, C. and Zimmermann, U.: Proteome analysis of renal cell carcinoma to develop new strategies in diagnosis and therapy. Int J of Clinical Pharmacology and Therapeutics 42, 635-636 (2004).
  • Zimmermann, U.; Balabanov, S.; Giebel, J.; Teller, S.; Junker, H.; Schmoll, D.; Protzel, C.; Scharf, C.; Kleist, B. and Walther, R.: Increased expression and altered location of annexin IV in renal clear cell carcinoma: a possible role in tumour dissemination. Cancer Lett. 209, 111-118 (2004).
  • Höper, D.; Völker, U. and Hecker, M.: Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis. J Bacteriol 187, 2810-2826 (2005).
  • Steil, L.; Serrano, M.; Henriques, A. O. and Völker, U.: Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis. Microbiology 151, 399-420 (2005).
  • Völker, U. and Hecker, M.: From genomics via proteomics to cellular physiology of the Gram-positive model organism Bacillus subtilis. Cell Microbiol 7, 1077-1085 (2005).
  • Zilhao, R.; Isticato, R.; Martins, L. O.; Steil, L.; Völker, U.; Ricca, E.; Moran, C. P., Jr. and Henriques, A. O.: Assembly and function of a spore coat-associated transglutaminase of Bacillus subtilis. J Bacteriol 187, 7753-7764 (2005).
  • Brigulla, M.; Thiele, T.; Scharf, C.; Breitner-Ruddock, S.; Venz, S.; Völker, U. and Greinacher, A.: Proteomics as a tool for assessment of therapeutics in transfusion medicine: evaluation of prothrombin complex concentrates. Transfusion 46, 377-385 (2006).
  • Budde, I.; Steil, L.; Scharf, C.; Völker, U. and Bremer, E.: Adaptation of Bacillus subtilis to growth at low temperature: a combined transcriptomic and proteomic appraisal. Microbiology 152, 831-853 (2006).
  • Hecker, M. and Völker, U. (2006). Towards a comprehensive understanding of Bacillus subtilis cell physiology by physiological proteomics. In Proteomics of Microbial Pathogens (Jungblut, P.andHecker, M., eds.), pp. 31-62. Wiley VCH, Weinheim.
  • Hoffrogge, R.; Beyer, S.; Völker, U.; Uhrmacher, A. M. and Rolfs, A.: 2-DE proteomic profiling of neuronal stem cells. Neurodegener Dis 3, 112-121 (2006).
  • Hoffrogge, R.; Mikkat, S.; Scharf, C.; Beyer, S.; Christoph, H.; Pahnke, J.; Mix, E.; Berth, M.; Uhrmacher, A.; Zubrzycki, I. Z.; Miljan, E.; Völker, U. and Rolfs, A.: 2-DE proteome analysis of a proliferating and differentiating human neuronal stem cell line (ReNcell VM). Proteomics 6, 1833-1847 (2006).
  • Martin, H. J.; Breyer-Pfaff, U.; Wsol, V.; Venz, S.; Block, S. and Maser, E.: Purification and characterization of akr1b10 from human liver: role in carbonyl reduction of xenobiotics. Drug Metab Dispos 34, 464-470 (2006).
  • Meyer Zu Schwabedissen, H. E.; Dreisbach, A.; Hammer, E.; Fusch, C.; Hecker, M.; Völker, U. and Kroemer, H. K.: Direct mass spectrometric identification of ABCB1 (P-glycoprotein/MDR1) from the apical membrane fraction of human placenta using fourier transform ion cyclotron mass spectrometry. Pharmacogenet Genomics 16, 385-389 (2006).
  • Meyer zu Schwabedissen, H. E.; Grube, M.; Dreisbach, A.; Jedlitschky, G.; Meissner, K.; Linnemann, K.; Fusch, C.; Ritter, C. A.; Völker, U. and Kroemer, H. K.: Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of abcg2 (bcrp). Drug Metab Dispos 34, 524-533 (2006).
  • Mikolasch, A.; Niedermeyer, T. H.; Lalk, M.; Witt, S.; Seefeldt, S.; Hammer, E.; Schauer, F.; Gesell, M.; Hessel, S.; Julich, W. D. and Lindequist, U.: Novel penicillins synthesized by biotransformation using laccase from Trametes spec. Chem Pharm Bull (Tokyo) 54, 632-638 (2006).
  • Saparrat, M. C. and Hammer, E.: Decolorization of synthetic dyes by the deuteromycete Pestalotiopsis guepinii CLPS no. 786 strain. J Basic Microbiol 46, 28-33 (2006).
  • Sietmann, R.; Gesell, M.; Hammer, E. and Schauer, F.: Oxidative ring cleavage of low chlorinated biphenyl derivatives by fungi leads to the formation of chlorinated lactone derivatives. Chemosphere 64, 672-685 (2006).
  • Beyer, S.; Mix, E.; Hoffrogge, R.; Lünser, K.; Völker, U. and Rolfs, A.: Neuroproteomics in stem cell differentiation. Clinical Proteomics, in press. (2007).
  • Bien, S.; Riad, A.; Ritter, C. A.; Gratz, M.; Olshausen, F.; Westermann, D.; Grube, M.; Krieg, T.; Ciecholewski, S.; Felix, S. B.; Staudt, A.; Schultheiss, H. P.; Ewert, R.; Völker, U.; Tschope, C. and Kroemer, H. K.: The Endothelin Receptor Blocker Bosentan Inhibits Doxorubicin-Induced Cardiomyopathy. Cancer Res 67, 10428-10435 (2007).
  • Costa, T.; Serrano, M.; Steil, L.; Völker, U.; Moran, C. P., Jr. and Henriques, A. O.: The timing of cotE expression affects Bacillus subtilis spore coat morphology but not lysozyme resistance. J Bacteriol 189, 2401-2410 (2007).
  • Grabarczyk, P.; Przybylski, G. K.; Depke, M.; Volker, U.; Bahr, J.; Assmus, K.; Broker, B. M.; Walther, R. and Schmidt, C. A.: Inhibition of BCL11B expression leads to apoptosis of malignant but not normal mature T cells. Oncogene 26, 3797-3810 (2007).
  • Hecker, M.; Pane-Farre, J. and Völker, U.: SigB-dependent general stress response in Bacillus subtilis and related gram-positive bacteria. Annu Rev Microbiol 61, 215-236 (2007).
  • Hoffrogge, R.; Beyer, S.; Hubner, R.; Mikkat, S.; Mix, E.; Scharf, C.; Schmitz, U.; Pauleweit, S.; Berth, M.; Zubrzycki, I. Z.; Christoph, H.; Pahnke, J.; Wolkenhauer, O.; Uhrmacher, A.; Völker, U. and Rolfs, A.: 2-DE profiling of GDNF overexpression-related proteome changes in differentiating ST14A rat progenitor cells. Proteomics 7, 33-46 (2007).
  • Junker, H.; Suofu, Y.; Venz, S.; Sascau, M.; Herndon, J. G.; Kessler, C.; Walther, R. and Popa-Wagner, A.: Proteomic identification of an upregulated isoform of annexin A3 in the rat brain following reversible cerebral ischemia. Glia 55, 1630-1637 (2007).
  • Kallwellis-Opara, A.; Staudt, A.; Trimpert, C.; Noutsias, M.; Kühl, U.; Pauschinger, M.; Schultheiss, H. P.; Grube, M.; Böhm, M.; Baumann, G.; Völker, U.; Kroemer, H. K. and Felix, S. B.: Immunoadsorption and subsequent immunoglobulin substitution decreases myocardial gene expression of desmin in dilated cardiomyopathy. J Mol Med 85, 1429-1435 (2007).
  • Kumar, K. S.; Sonnemann, J.; Hong Le, T. T.; Buurman, C.; Adler, F.; Maass, M.; Völker, U. and Beck, J. F.: Histone deacetylase inhibitors, but not vincristine, cooperate with radiotherapy to induce cell death in medulloblastoma. Anticancer Res 27, 465-470 (2007).
  • Mäder, U.; Homuth, G.; Völker, U. and Hecker, M. (2007). Global regulatory systems mediating general starvation responses in Bacillus subtilis. In Global Regulatory Networks in Bacillus subtilis (Fujita, Y., ed.), pp. 205-228. Transworld Research Network, Kerala, India.
  • Manda, K.; Gordes, D.; Mikolasch, A.; Hammer, E.; Schmidt, E.; Thurow, K. and Schauer, F.: Carbon-oxygen bond formation by fungal laccases: cross-coupling of 2,5-dihydroxy-N-(2-hydroxyethyl)-benzamide with the solvents water, methanol, and other alcohols. Appl Microbiol Biotechnol 76, 407-416 (2007).
  • Mikolasch, A.; Niedermeyer, T. H.; Lalk, M.; Witt, S.; Seefeldt, S.; Hammer, E.; Schauer, F.; Gesell Salazar, M.; Hessel, S.; Julich, W. D. and Lindequist, U.: Novel cephalosporins synthesized by amination of 2,5-dihydroxybenzoic acid derivatives using fungal laccases II. Chem Pharm Bull (Tokyo) 55, 412-416 (2007).
  • Reeves, A.; Gerth, U.; Völker, U. and Haldenwang, W. G.: ClpP modulates the activity of the Bacillus subtilis stress response transcription factor, SigB. J Bacteriol 189, 6168-6175 (2007).
  • Sonnemann, J.; Dreyer, L.; Hartwig, M.; Palani, C. D.; Hong le, T. T.; Klier, U.; Bröker, B.; Völker, U. and Beck, J. F.: Histone deacetylase inhibitors induce cell death and enhance the apoptosis-inducing activity of TRAIL in Ewing's sarcoma cells. J Cancer Res Clin Oncol 133, 847-858 (2007).
  • Thiele, T.; Steil, L.; Gebhard, S.; Scharf, C.; Hammer, E.; Brigulla, M.; Lubenow, N.; Clemetson, K. J.; Völker, U. and Greinacher, A.: Profiling of alterations in platelet proteins during storage of platelet concentrates. Transfusion 47, 1221-1233 (2007).
  • Thiele, T.; Steil, L.; Völker, U. and Greinacher, A.: Proteomics of blood-based therapeutics: a promising tool for quality assurance in transfusion medicine. BioDrugs 21, 179-193 (2007).
  • Depke, M.; Fusch, G.; Domanska, G.; Geffers, R.; Völker, U.; Schütt, C. and Kiank, C.: Hypermetabolic syndrome as a consequence of repeated psychological stress in mice. Endocrinology 149, 2714-2723 (2008).
  • Dreisbach, A.; Otto, A.; Becher, D.; Hammer, E.; Teumer, A.; Gouw, J. W.; Hecker, M. and Völker, U.: Monitoring of changes in the membrane proteome during stationary phase adaptation of Bacillus subtilis using in vivo labeling techniques. Proteomics 8, 2062-2076 (2008).
  • Eichstaedt, S.; Gabler, K.; Below, S.; Muller, C.; Kohler, C.; Engelmann, S.; Hildebrandt, P.; Völker, U.; Hecker, M. and Hildebrandt, J. P.: Effects of Staphylococcus aureus-hemolysin A on calcium signalling in immortalized human airway epithelial cells. Cell Calcium (2008).
  • Grumann, D.; Scharf, S. S.; Holtfreter, S.; Kohler, C.; Steil, L.; Engelmann, S.; Hecker, M.; Völker, U. and Bröker, B. M.: Immune cell activation by enterotoxin gene cluster (egc)-encoded and non-egc superantigens from Staphylococcus aureus. J Immunol 181, 5054-5061 (2008).
  • Landsberger, M.; Staudt, A.; Choudhury, S.; Trimpert, C.; Herda, L. R.; Klingel, K.; Kandolf, R.; Schultheiss, H. P.; Kroemer, H. K.; Völker, U. and Felix, S. B.: Potential role of antibodies against cardiac Kv channel-interacting protein 2 in dilated cardiomyopathy. Am Heart J 156, 92-99 e92 (2008).
  • Mikolasch, A.; Hessel, S.; Salazar, M. G.; Neumann, H.; Manda, K.; Gordes, D.; Schmidt, E.; Thurow, K.; Hammer, E.; Lindequist, U.; Beller, M. and Schauer, F.: Synthesis of new N-analogous corollosporine derivatives with antibacterial activity by laccase-catalyzed amination. Chem Pharm Bull (Tokyo) 56, 781-786 (2008).
  • Mikolasch, A.; Wurster, M.; Lalk, M.; Witt, S.; Seefeldt, S.; Hammer, E.; Schauer, F.; Julich, W. D. and Lindequist, U.: Novel beta-lactam antibiotics synthesized by amination of catechols using fungal laccase. Chem Pharm Bull (Tokyo) 56, 902-907 (2008).
  • Röhl, C.; Armbrust, E.; Kolbe, K.; Lucius, R.; Maser, E.; Venz, S. and Gulden, M.: Activated microglia modulate astroglial enzymes involved in oxidative and inflammatory stress and increase the resistance of astrocytes to oxidative stress in Vitro. Glia 56, 1114-1126 (2008).
  • Sonnemann, J.; Huls, I.; Sigler, M.; Palani, C. D.; Hong le, T. T.; Völker, U.; Kroemer, H. K. and Beck, J. F.: Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells. Oncol Rep 20, 219-224 (2008).
  • Steil, L.; Thiele, T.; Hammer, E.; Bux, J.; Kalus, M.; Volker, U. and Greinacher, A.: Proteomic characterization of freeze-dried human plasma: providing treatment of bleeding disorders without the need for a cold chain. Transfusion 48, 2356-2363 (2008).
  • Ummanni, R.; Junker, H.; Zimmermann, U.; Venz, S.; Teller, S.; Giebel, J.; Scharf, C.; Woenckhaus, C.; Dombrowski, F. and Walther, R.: Prohibitin identified by proteomic analysis of prostate biopsies distinguishes hyperplasia and cancer. Cancer Lett 266, 171-185 (2008).
  • Aakvik, T.; Degnes, K. F.; Dahlsrud, R.; Schmidt, F.; Dam, R.; Yu, L.; Völker, U.; Ellingsen, T. E. and Valla, S.: A plasmid RK2-based broad-host-range cloning vector useful for transfer of metagenomic libraries to a variety of bacterial species. FEMS Microbiol Lett 296, 149-158 (2009).
  • Bauer, L.; Venz, S.; Junker, H.; Brandt, R. and Radons, J.: Nicotinamide phosphoribosyltransferase and prostaglandin H2 synthase 2 are up-regulated in human pancreatic adenocarcinoma cells after stimulation with interleukin-1. Int J Oncol 35, 97-107 (2009).
  • Commichau, F. M.; Rothe, F. M.; Herzberg, C.; Wagner, E.; Hellwig, D.; Lehnik-Habrink, M.; Hammer, E.; Völker, U. and Stülke, J.: Novel activities of glycolytic enzymes in Bacillus subtilis: interactions with essential proteins involved in mRNA processing. Mol Cell Proteomics 8, 1350-1360 (2009).
  • Depke, M.; Steil, L.; Domanska, G.; Völker, U.; Schütt, C. and Kiank, C.: Altered hepatic mRNA expression of immune response and apoptosis-associated genes after acute and chronic psychological stress in mice. Mol. Immunol. 46, 3018-3028 (2009).
  • Eichstaedt, S.; Gabler, K.; Below, S.; Müller, C.; Kohler, C.; Engelmann, S.; Hildebrandt, P.; Völker, U.; Hecker, M. and Hildebrandt, J. P.: Effects of Staphylococcus aureus-hemolysin A on calcium signalling in immortalized human airway epithelial cells. Cell Calcium 45, 165-176 (2009).
  • Grisk, O.; Steinbach, A. C.; Ciecholewski, S.; Schlüter, T.; Kloting, I.; Schmidt, H.; Dazert, E.; Schaeffeler, E.; Steil, L.; Gauer, S.; Jedlitschky, G.; Schwab, M.; Geisslinger, G.; Hauser, I. A.; Völker, U.; Kroemer, H. K. and Rettig, R.: Multidrug resistance-related protein 2 genotype of the donor affects kidney graft function. Pharmacogenet Genomics 19, 276-288 (2009).
  • Heine, F.; Stahl, F.; Strauber, H.; Wiacek, C.; Benndorf, D.; Repenning, C.; Schmidt, F.; Scheper, T.; von Bergen, M.; Harms, H. and Muller, S.: Prediction of flocculation ability of brewing yeast inoculates by flow cytometry, proteome analysis, and mRNA profiling. Cytometry A 75, 140-147 (2009).
  • Jehmlich, N.; Schmidt, F.; Taubert, M.; Seifert, J.; von Bergen, M.; Richnow, H. H. and Vogt, C.: Comparison of methods for simultaneous identification of bacterial species and determination of metabolic activity by protein-based stable isotope probing (Protein-SIP) experiments. Rapid Commun Mass Spectrom 23, 1871-1878 (2009).
  • Kolz, M.; Johnson, T.; Sanna, S.; Teumer, A.; Vitart, V.; Perola, M.; Mangino, M.; Albrecht, E.; Wallace, C.; Farrall, M.; Johansson, A.; Nyholt, D. R.; Aulchenko, Y.; Beckmann, J. S.; Bergmann, S.; Bochud, M.; Brown, M.; Campbell, H.; Connell, J.; Dominiczak, A.; Homuth, G.; Lamina, C.; McCarthy, M. I.; Meitinger, T.; Mooser, V.; Munroe, P.; Nauck, M.; Peden, J.; Prokisch, H.; Salo, P.; Salomaa, V.; Samani, N. J.; Schlessinger, D.; Uda, M.; Völker, U.; Waeber, G.; Waterworth, D.; Wang-Sattler, R.; Wright, A. F.; Adamski, J.; Whitfield, J. B.; Gyllensten, U.; Wilson, J. F.; Rudan, I.; Pramstaller, P.; Watkins, H.; Doering, A.; Wichmann, H. E.; Spector, T. D.; Peltonen, L.; Volzke, H.; Nagaraja, R.; Vollenweider, P.; Caulfield, M.; Illig, T. and Gieger, C.: Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet 5, e1000504 (2009).
  • Rameshwaram, N. R.; Karanam, N. K.; Scharf, C.; Völker, U. and Nadimpalli, S. K.: Complete primary structure of a newly characterized galactose-specific lectin from the seeds of Dolichos lablab. Glycoconj J 26, 161-172 (2009).
  • Schmidt, F.; Fiege, T.; Hustoft, H. K.; Kneist, S. and Thiede, B.: Shotgun mass mapping of Lactobacillus species and subspecies from caries related isolates by MALDI-MS. Proteomics 9, 1994-2003 (2009).
  • Schmidt, F.; Schmid, M.; Thiede, B.; Pleissner, K. P.; Bohme, M. and Jungblut, P. R.: Assembling proteomics data as a prerequisite for the analysis of large scale experiments. Chem Cent J 3, 2 (2009).
  • Vasan, R. S.; Glazer, N. L.; Felix, J. F.; Lieb, W.; Wild, P. S.; Felix, S. B.; Watzinger, N.; Larson, M. G.; Smith, N. L.; Dehghan, A.; Grosshennig, A.; Schillert, A.; Teumer, A.; Schmidt, R.; Kathiresan, S.; Lumley, T.; Aulchenko, Y. S.; Konig, I. R.; Zeller, T.; Homuth, G.; Struchalin, M.; Aragam, J.; Bis, J. C.; Rivadeneira, F.; Erdmann, J.; Schnabel, R. B.; Dorr, M.; Zweiker, R.; Lind, L.; Rodeheffer, R. J.; Greiser, K. H.; Levy, D.; Haritunians, T.; Deckers, J. W.; Stritzke, J.; Lackner, K. J.; Völker, U.; Ingelsson, E.; Kullo, I.; Haerting, J.; O'Donnell, C. J.; Heckbert, S. R.; Stricker, B. H.; Ziegler, A.; Reffelmann, T.; Redfield, M. M.; Werdan, K.; Mitchell, G. F.; Rice, K.; Arnett, D. K.; Hofman, A.; Gottdiener, J. S.; Uitterlinden, A. G.; Meitinger, T.; Blettner, M.; Friedrich, N.; Wang, T. J.; Psaty, B. M.; van Duijn, C. M.; Wichmann, H. E.; Munzel, T. F.; Kroemer, H. K.; Benjamin, E. J.; Rotter, J. I.; Witteman, J. C.; Schunkert, H.; Schmidt, H.; Volzke, H. and Blankenberg, S.: Genetic Variants Associated With Cardiac Structure and Function: A Meta-analysis and Replication of Genome-wide Association Data. JAMA 302, 168-178 (2009).
  • Mohr, H.; Stei, L.; Gravemann, U.; Thiele, T.; Hammer, E.; Greinacher, A.; Müller, T. H. and Völker, U.: A novel approach to pathogen reduction in platelet concentrates using UVC light. Transfusion, 49, 2612-2624 (2009).
  • Newton-Cheh, C.; Johnson, T.; Gateva, V.; Tobin, M. D.; Bochud, M.; Coin, L.; Najjar, S. S.; Zhao, J. H.; Heath, S. C.; Eyheramendy, S.; Papadakis, K.; Voight, B. F.; Scott, L. J.; Zhang, F.; Farrall, M.; Tanaka, T.; Wallace, C.; Chambers, J. C.; Khaw, K. T.; Nilsson, P.; van der Harst, P.; Polidoro, S.; Grobbee, D. E.; Onland-Moret, N. C.; Bots, M. L.; Wain, L. V.; Elliott, K. S.; Teumer, A.; Luan, J.; Lucas, G.; Kuusisto, J.; Burton, P. R.; Hadley, D.; McArdle, W. L.; Brown, M.; Dominiczak, A.; Newhouse, S. J.; Samani, N. J.; Webster, J.; Zeggini, E.; Beckmann, J. S.; Bergmann, S.; Lim, N.; Song, K.; Vollenweider, P.; Waeber, G.; Waterworth, D. M.; Yuan, X.; Groop, L.; Orho-Melander, M.; Allione, A.; Di Gregorio, A.; Guarrera, S.; Panico, S.; Ricceri, F.; Romanazzi, V.; Sacerdote, C.; Vineis, P.; Barroso, I.; Sandhu, M. S.; Luben, R. N.; Crawford, G. J.; Jousilahti, P.; Perola, M.; Boehnke, M.; Bonnycastle, L. L.; Collins, F. S.; Jackson, A. U.; Mohlke, K. L.; Stringham, H. M.; Valle, T. T.; Willer, C. J.; Bergman, R. N.; Morken, M. A.; Doring, A.; Gieger, C.; Illig, T.; Meitinger, T.; Org, E.; Pfeufer, A.; Wichmann, H. E.; Kathiresan, S.; Marrugat, J.; O'Donnell, C. J.; Schwartz, S. M.; Siscovick, D. S.; Subirana, I.; Freimer, N. B.; Hartikainen, A. L.; McCarthy, M. I.; O'Reilly, P. F.; Peltonen, L.; Pouta, A.; de Jong, P. E.; Snieder, H.; van Gilst, W. H.; Clarke, R.; Goel, A.; Hamsten, A.; Peden, J. F., et al.: Genome-wide association study identifies eight loci associated with blood pressure. Nat. Genet, 41, 666-676 (2009).
  • Soranzo N; Spector TD; Mangino M; Kühnel B; Rendon A; Teumer A; Willenborg C; Wright B; Chen L; Li M; Salo P; Voight BF; Burns P; Laskowski RA; Xue Y; Menzel S; Altshuler D; Bradley JR; Bumpstead S; Burnett MS; Devaney J; Döring A; Elosua R; Epstein SE; Erber W; Falchi M; Garner SF; Ghori MJ; Goodall AH; Gwilliam R; Hakonarson HH; Hall AS; Hammond N; Hengstenberg C; Illig T; König IR; Knouff CW; McPherson R; Melander O; Mooser V; Nauck M; Nieminen MS; O'Donnell CJ; Peltonen L; Potter SC; Prokisch H; Rader DJ; Rice CM; Roberts R; Salomaa V; Sambrook J; Schreiber S; Schunkert H; Schwartz SM; Serbanovic-Canic J; Sinisalo J; Siscovick DS; Stark K; Surakka I; Stephens J; Thompson JR; Völker U; Völzke H; Watkins NA; Wells GA; Wichmann HE; Van Heel DA; Tyler-Smith C; Thein SL; Kathiresan S; Perola M; Reilly MP; Stewart AF; Erdmann J; Samani NJ; Meisinger C; Greinacher A; Deloukas P; Ouwehand WH; Gieger C.: A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat Genet. 41, 1182-1190 (2009).
  • Holtfreter; S.; Nguyen; T.T.; Wertheim; H.; Steil; L.; Kusch; H.; Truong; Q.P;; Engelmann; S.; Hecker; M.; Völker; U.; van Belkum; A.; Bröker; B.M.: Human immune proteome in experimental colonization with Staphylococcus aureus. Clin Vaccine Immunol. 16; 1607-1614 (2009).
  • Farajzadeh Deroee; A.; Oweinah; J.; Naraghi; M.; Hosemann; W.; Athari; B.; Völker; U.; Scharf; C.: Regression of polypoid nasal mucosa after systemic corticosteroid therapy: a proteomics study. Am J Rhinol Allergy. 23; 480-485 (2009).
  • Becher, D.; Hempel, K.; Sievers, S.; Zühlke, D.; Pané-Farré, J.; Otto, A.; Fuchs, S.; Albrecht, D.; Bernhardt, J.; Engelmann, S.; Völker, U.; van Dijl, J. M. and Hecker, M.: A proteomic view of an important human pathogen - Towards the quantification of the entire Staphylococcus aureus proteome. PLoS ONE 4, e8176 (2009).
  • Hauberg, L.; Schmidt, F.; Scharf, C.; Dörr, J.; Völker, U:, Reinhold-Hurek, B.: Proteomic characterization of a pilR regulatory mutant of Azoarcus sp. strain BH72 with the aid of gel-based and gel-free approaches. Proteomics. 10, 458-469 (2010).
  • Venner, M.; Peters, J.; Höhensteiger, N.; Schock, B.; Bornhorst, A.; Grube, M.; Adam, U.; Scheuch, E.; Weitschies, W.; Rosskopf, D.; Kroemer, H.K.; Siegmund, W.: Concentration of the macrolide antibiotic tulathromycin in broncho-alveolar cells is influenced by comedication of rifampicin in foals. Naunyn Schmiedebergs Arch Pharmacol. 381, 161-169 (2010).
  • Hammer, E.; Bien, S.; Salazar, M.G.; Steil, L.; Scharf, C.; Hildebrandt, P.; Schroeder, H.W.; Kroemer, H.K.; Völker, U.; Ritter, C.A.: Proteomic analysis of doxorubicin-induced changes in the proteome of HepG2cells combining 2-D DIGE and LC-MS/MS approaches. Proteomics. 10, 99-114 (2010).
  • Köttgen, A.; Pattaro, C.; Böger, C.A.; Fuchsberger, C.; Olden, M.; Glazer, N.L.; Parsa, A.; Gao, X.; Yang, Q.; Smith, A.V.; O'Connell, J.R.; Li, M.; Schmidt, H.; Tanaka, T.; Isaacs, A.; Ketkar, S.; Hwang, S.J.; Johnson, A.D.; Dehghan, A.; Teumer, A.; Paré, G.; Atkinson, E.J.; Zeller, T.; Lohman, K.; Cornelis, M.C.; Probst-Hensch, N.M.; Kronenberg, F.; Tönjes, A.; Hayward, C.; Aspelund, T.; Eiriksdottir, G.; Launer, L.J.; Harris, T.B.; Rampersaud, E.; Mitchell, B.D.; Arking, D.E.; Boerwinkle, E.; Struchalin, M.; Cavalieri, M.; Singleton, A.; Giallauria, F.; Metter, J.; de Boer, I.H.; Haritunians, T.; Lumley, T.; Siscovick, D.; Psaty, B..M.; Zillikens, M.C.; Oostra, B.A.; Feitosa, M.; Province, M.; de Andrade, M.; Turner, S.T.; Schillert, A.; Ziegler, A.; Wild, P.S.; Schnabel, R.B.; Wilde, S.; Munzel, T.F.; Leak, T.S.; Illig, T.; Klopp, N.; Meisinger, C.; Wichmann, H.E.; Koenig, W.; Zgaga, L.; Zemunik, T.; Kolcic, I.; Minelli, C.; Hu, F.B.; Johansson, A.; Igl, W.; Zaboli, G.; Wild, S,H.; Wright, A.F.; Campbell, H.; Ellinghaus, D.; Schreiber, S.; Aulchenko, Y.S.; Felix, J.F.; Rivadeneira, F.; Uitterlinden, A.G.; Hofman, A.; Imboden, M.; Nitsch, D.; Brandstätter, A.; Kollerits, B.; Kedenko, L.; Mägi, R.; Stumvoll, M.; Kovacs, P.; Boban, M.; Campbell, S.; Endlich, K.; Völzke, H.; Kroemer, H.K.; Nauck, M.; Völker, U.; Polasek, O.; Vitart, V.; Badola, S.; Parker, A.N.; Ridker, P.M.; Kardia, S.L.; Blankenberg, S.; Liu, Y.; Curhan, G.C.; Franke, A.; Rochat, T.; Paulweber, B.; Prokopenko, I.; Wang, W.; Gudnason, V.; Shuldiner, A.R.; Coresh, J.; Schmidt, R.; Ferrucci, L.; Shlipak, M.G.; van Duijn, C.M.; Borecki, I.; Krämer, B.K.; Rudan, I.; Gyllensten, U.; Wilson, J.F.; Witteman, J.C.; Pramstaller, P.P.; Rettig, R.; Hastie, N.; Chasman, D.I.; Kao, W.H.; Heid, I.M.; Fox, C.S.: New loci associated with kidney function and chronic kidney disease. Nat Genet. 42, 376-384 (2010).
  • Hammer, E.; Phong, T.Q.; Steil, L.; Klingel, K.; Salazar, M.G.; Bernhardt, J.; Kandolf, R.; Kroemer, H.K.; Felix, S.B.; Völker, U.: Viral myocarditis induced by Coxsackievirus B3 in A.BY/SnJ mice: analysis of changes in the myocardial proteome. Proteomics. 10, 1802-1818 (2010).
  • Köck, K.; Koenen, A.; Giese, B.; Fraunholz, M.; May, K.; Siegmund, W.; Hammer, E.; Völker, U.; Jedlitschky, G.; Kroemer, H.K.; Grube, M.: Rapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization. J Biol Chem. 285, 11336-11347 (2010).
  • Greinacher, A.; Wesche, J.; Hammer, E.; Fürll, B.; Völker, U.; Reil, A.; Bux, J.: Characterization of the human neutrophil alloantigen-3a. Nat Med. 16, 45-48 (2010).
  • Jedlitschky, G.; Cattaneo, M.; Lubenow, L.E.; Rosskopf, D.; Lecchi, A.; Artoni, A.; Motta, G.; Niessen, J.; Kroemer, H.K.; Greinacher, A.: Role of MRP4 (ABCC4) in platelet adenine nucleotide-storage: evidence from patients with delta-storage pool deficiencies. Am J Pathol. 176, 1097-1103 (2010).
  • Sotoodehnia N; Isaacs A; de Bakker PI; Dörr M; Newton-Cheh C; Nolte IM; van der Harst P; Müller M; Eijgelsheim M; Alonso A; Hicks AA; Padmanabhan S; Hayward C; Smith AV; Polasek O; Giovannone S; Fu J; Magnani JW; Marciante KD; Pfeufer A; Gharib SA; Teumer A; Li M; Bis JC; Rivadeneira F; Aspelund T; Köttgen A; Johnson T; Rice K; Sie MP; Wang YA; Klopp N; Fuchsberger C; Wild SH; Mateo Leach I; Estrada K; Völker U; Wright AF; Asselbergs FW; Qu J; Chakravarti A; Sinner MF; Kors JA; Petersmann A; Harris TB; Soliman EZ; Munroe PB; Psaty BM; Oostra BA; Cupples LA; Perz S; de Boer RA; Uitterlinden AG; Völzke H; Spector TD; Liu FY; Boerwinkle E; Dominiczak AF; Rotter JI; van Herpen G; Levy D; Wichmann HE; van Gilst WH; Witteman JC; Kroemer HK; Kao WH; Heckbert SR; Meitinger T; Hofman A; Campbell H; Folsom AR; van Veldhuisen DJ; Schwienbacher C; O'Donnell CJ; Volpato CB; Caulfield MJ; Connell JM; Launer L; Lu X; Franke L; Fehrmann RS; te Meerman G; Groen HJ; Weersma RK; van den Berg LH; Wijmenga C; Ophoff RA; Navis G; Rudan I; Snieder H; Wilson JF; Pramstaller PP; Siscovick DS; Wang TJ; Gudnason V; van Duijn CM; Felix SB; Fishman GI; Jamshidi Y; Stricker BH; Samani NJ; Kääb S; Arking DE.: Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet. 42, 1068-1076 (2010).
  • Grabarczyk, P.; Nähse, V.; Delin, M.; Przybylski, G.; Depke, M.; Hildebrandt, P.; Völker, U.; Schmidt, C.A.: Increased expression of bcl11b leads to chemoresistance accompanied by G1 accumulation. PLoS One. 5, e12532 (2010).
  • Jehmlich, N.; Hübschmann, T.; Gesell Salazar, M.; Völker, U.; Benndorf, D.; Müller, S.; von Bergen, M.; Schmidt, F.: Advanced tool for characterization of microbial cultures by combining cytomics and proteomics. Appl Microbiol Biotechnol. 88, 575-584 (2010).
  • Liebal, U.W.; Millat, T.; De Jong, I.G.; Kuipers, O.P.; Völker, U.; Wolkenhauer, O.: How mathematical modelling elucidates signalling in Bacillus subtilis. Mol Microbiol. 77, 1083-1095 (2010).
  • Thiele, T.; Steil, L.; Völker, U.; Greinacher, A.: Transfusion medicine and proteomics. Alliance or coexistence? Blood Transfus. 8, 16-25 (2010).
  • Schmidt, F.; Scharf, S.S.; Hildebrandt, P.; Burian, M.; Bernhardt, J.; Dhople, V.; Kalinka, J.; Gutjahr, M.; Hammer, E.; Völker, U.: Time-resolved quantitative proteome profiling of host-pathogen interactions: the response of Staphylococcus aureus RN1HG to internalisation by human airway epithelial cells. Proteomics. 10, 2801-2811 (2010).
  • Karanam, N.K,; Grabarczyk, P.; Hammer, E.; Scharf, C.; Venz, S.; Gesell-Salazar, M.; Barthlen, W.; Przybylski, G.K.; Schmidt, C.A.; Völker, U.: Proteome analysis reveals new mechanisms of Bcl11b-loss driven apoptosis. J Proteome Res. 9, 3799-3811 (2010).
  • Liebeke, M.; Dörries, K.; Zühlke, D.; Bernhardt, J.; Fuchs, S.; Pané-Farré, J.; Engelmann, S.; Völker, U.; Bode, R.; Dandekar, T.; Lindequis,t U.; Hecker, M.; Lalk, M.: A metabolomics and proteomics study of the adaptation of Staphylococcus aureus to glucose starvation. Mol Biosyst. 7, 1241-1253 (2011).
  • Frank, S.; Schmidt, F.; Klockgether, J.; Davenport, C.F.; Gesell Salazar, M.; Völker, U.; Tümmler, B.: Functional genomics of the initial phase of cold adaptation of Pseudomonas putida KT2440. FEMS Microbiol Lett. 318, 47-54 (2011).
  • Meyer, F.M.; Gerwig, J.; Hammer, E.; Herzberg, C.; Commichau, F.M.; Völker, U.; Stülke, J.: Physical interactions between tricarboxylic acid cycle enzymes in Bacillus subtilis: evidence for a metabolon. Metab Eng. 13, 18-27 (2011).
  • Teumer, A.; Rawal, R.; Homuth, G.; Ernst, F.; Heier, M.; Evert, M.; Dombrowski, F.; Völker, U.; Nauck, M.; Radke, D.; Ittermann, T.; Biffar, R.; Döring, A.; Gieger, C,; Klopp, N.; Wichmann, H.E.; Wallaschofski, H.; Meisinger, C.; Völzke, H.: Genome-wide Association Study Identifies Four Genetic Loci Associated with Thyroid Volume and Goiter Risk. Am J Hum Genet. 88, 664-673 (2011).
  • Holtfreter, S.; Jursa-Kulesza, J.; Masiuk, H.; Verkaik, N.J.; de Vogel, C.; Kolata, J.; Nowosiad, M.; Steil, L.; van Wamel, W.; van Belkum, A.; Völker, U.; Giedrys-Kalemba, S.; Bröker, B.M.: Antibody responses in furunculosis patients vaccinated with autologous formalin-killed Staphylococcus aureus. Eur J Clin Microbiol Infect Dis. 30, 707-717 (2011).
  • Hammer, E.; Goritzka, M.; Ameling, S.; Darm, K.; Steil, L.; Klingel, K.; Trimpert, C.; Herda, L,R.; Dörr, M.; Kroemer, H.K.; Kandolf, R.; Staudt, A.; Felix, S.B.; Völker, U.: Characterization of the Human Myocardial Proteome in Inflammatory Dilated Cardiomyopathy by Label-free Quantitative Shotgun Proteomics of Heart Biopsies. J Proteome Res. 10, 2161-2171 (2011).
  • Maass, S.; Sievers, S.; Zühlke, D.; Kuzinski, J.; Sappa, P.K.; Muntel, J.; Hessling, B.; Bernhardt, J.; Sietmann, R.; Völker, U,; Hecker, M.; Becher, D.: Efficient, global-scale quantification of absolute protein amounts by integration of targeted mass spectrometry and two-dimensional gel-based proteomics. Anal Chem. 83, 2677-2684 (2011).
  • Völzke, H.; Alte, D.; Schmidt, C.O.; Radke, D.; Lorbeer, R,; Friedrich, N.; Aumann, N.; Lau, K.; Piontek, M.; Born, G.; Havemann, C.; Ittermann, T.; Schipf, S.; Haring, R.; Baumeister, S.E.; Wallaschofski, H.; Nauck, M.; Frick, S.; Arnold, A.; Jünger, M.; Mayerle, J.; Kraft, M.; Lerch, M,M.; Dörr, M.; Reffelmann, T.; Empen, K.; Felix, S.B.; Obst, A.; Koch, B.; Gläser S.; Ewert, R.; Fietze, I.; Penzel, T.; Dören, M.; Rathmann, W.; Haerting, J.; Hannemann, M.; Röpcke, J.; Schminke, U.; Jürgens, C.; Tost, F.; Rettig, R.; Kors, J.A.; Ungerer, S.; Hegenscheid, K.; Kühn, J.P.; Kühn, J.; Hosten, N.; Puls, R.; Henke, J.; Gloger, O.; Teumer, A.; Homuth, G.; Völker, U.; Schwahn, C.; Holtfreter, B.; Polzer, I.; Kohlmann, T.; Grabe, H.J.; Rosskopf, D.; Kroemer, H.K.; Kocher, T.; Biffar, R.; John, U.; Hoffmann, W.: Cohort profile: the study of health in pomerania. Int J Epidemiol. 40, 294-307 (2011).
  • Suhre; K.; Wallaschofski; H.; Raffler; J.; Friedrich; N.; Haring; R.; Michael; K.; Wasner; C.; Krebs; A.; Kronenberg; F.; Chang; D.; Meisinger; C.; Wichmann; H.E.; Hoffmann; W.; Völzke; H.; Völker; U.; Teumer; A.; Biffar; R.; Kocher; T.; Felix; S.B.; Illig; T.; Kroemer; H.K.; Gieger; C.; Römisch-Margl; W.; Nauck; M.: A genome-wide association study of metabolic traits in human urine. Nat Genet. in press (2011)