Mitarbeiter der Klinik

Prof. Dr. Johannes Hertel



 03834 86-6907


Qualifikation/Funktion:Professor (W1) in Systems Biology and Translation in Psychiatry

Department of Psychiatry and Psychotherapy



Research career

  • Feb 2021 - present | W1 Tenure Track Professor for Systems Biology and Translational Psychiatry, University Medicine Greifswald
  • Feb 2019 – Nov 2020 | Postdoctoral Research Fellow at the National University of Ireland, Galway, Thiele lab
  • Aug 2018-Jan 2019 | Post-doctoral researcher at the Luxembourg Center for Systems Biology, Thiele lab
  • Jan 2014–Jan 2021 | Researcher at the University medicine Greifswald
  • Mar 2013– Sep 2017     Statistician (Research Assistant and Researcher) at the German Center for Neurodegenerative Diseases, site Greifswald/Rostock Germany; Study statistician for the DelpHi-Trial
  • Sep 2012–Mar 2014 | Software Engineer (Research Assistant) at the Far University Hagen, Institute for Psychology
  • Jul 2011–Sep 2012 | Statistical Programmer (Research Assistant) at the Institute for Employment Research Nord, Kiel
  • Oct 2010–Sep 2012 | Lecturer (Wissenschaftlicher Mitarbeiter mit überwiegender Tätigkeit in der Lehre und Lehrbeauftragter) at the Christian-Albrechts-University Kiel, Institute for Psychology

University Training

  • 2012 - 2014 | Biomathematics, University of Greifswald
  • 2004 - 2010 | Diploma, Psychology, University of Kiel

Awards and honoraries

2019 | Promotionspreis der Universität Greifswald 2018/2019 (Dissertation award of the University Greifswald)

Since 2021 | Young Academy Fellow of the Academy of Sciences and Humanities in Hamburg

Ongoing grants

2022 | Towards a universal characterization of human aging 1: Immunosenescence (Impetus Grants), together with Alan Cohen (University of Sherbrooke), Michael Gurven (University of California-Santa Barbara). Maël Lemoine (University of Bordeaux), Tamàs Fülöp (University of Sherbrooke).

2022 | Modelling the influence of the gut microbiome on patterns of brain aging in the general population by combining constraint-based modelling approaches with large cohort magnetic resonance imaging data. (DFG call “Sequencing costs in projects”), together with Dr. Fabian Frost (University Medicine Greifswald)

Selected Publications

  1. Baldini F*, Hertel J*, Sandt E, Thinnes CC, Neuberger-Castillo L, Pavelka L, u. a. Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions. BMC biology. 2020;18(1):1–21.
  2. Cheng Y, Schlosser P, Hertel J, Sekula P, Oefner PJ, Spiekerkoetter U, u. a. Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism. Nature communications. 2021;12(1):1–15.
  3. Heinken A, Basile A, Hertel J, Thinnes C, Thiele I. Genome-Scale Metabolic Modeling of the Human Microbiome in the Era of Personalized Medicine. Annu Rev Microbiol. 8. September 2021;75(1):annurev-micro-060221-012134.
  4. Hertel J, Fässler D, Heinken A, Weiß FU, Rühlemann M, Bang C, u. a. NMR Metabolomics Reveal Urine Markers of Microbiome Diversity and Identify Benzoate Metabolism as a Mediator between High Microbial Alpha Diversity and Metabolic Health. Metabolites. 31. März 2022;12(4):308.
  5. Hertel J, Frenzel S, Koenig J, Wittfeld K, Fuellen G, Holtfreter B, u. a. The informative error: a framework for the construction of individualized phenotypes. Statistical methods in medical research. 2019;28(5):1427–38.