Projektleitung Linda Schönborn

Anti-PF4-Immunothrombosen nach Impfungen und Infektionen

  • Longitudinal follow-up study on patients with vaccine-induced immune thrombotic thrombocytopenia and thrombosis syndrome (VITT/TTS) after vaccination against SARS-CoV-2 (DRKS00025738)
  • Investigation on the prevalence of anti-PF4 antibodies recognizing the binding site of VITT antibodies on PF4 and of anti-PF4/heparin antibodies recognizing the binding site of HIT antibodies in normal individuals and patients referred with the clinical suspicion of either HIT, or VITT, and in patients with thrombosis of unknown cause (DRKS00032653)

Einfluss des demografischen Wandels auf die Blutversorgung

  • Prospektive Longitudinalstudie zu Blutspende und Transfusionsbedarf in Mecklenburg-Vorpommern (Blut-MV Studie)

Ausgewählte Publikationen

  • Schönborn, L et al. Anti-PF4 immunothrombosis without proximate heparin or adenovirus vector vaccine exposure. Blood, 2023, 142(26), 2305-2314.
  • Schönborn, L et al. Long-term outcome in vaccine-induced immune thrombocytopenia and thrombosis. Journal of Thrombosis and Haemostasis, 2023, 21(9), 2519-2527.
  • Schönborn, L et al. SARS-CoV-2 Infection in Patients with a History of VITT. New England Journal of Medicine, 2022, 387(1), 88-90.
  • Salih, F, Schönborn, L et al. Vaccine-induced thrombocytopenia with severe headache. New England Journal of Medicine, 2021, 385(22), 2103-2105.
  • Schönborn, L et al. Decline in pathogenic antibodies over time in VITT. New England Journal of Medicine, 2021, 385(19), 1815-1816.
  • Schönborn L et al. Characteristics of Recipients of Red Blood Cell Concentrates in a German Federal State. Transfus Med Hemother. 2020;47(5):370-8.
  • Greinacher A et al.: Zusammenarbeit aller Krankenhäuser in Mecklenburg-Vorpommern ermöglicht eine deutschlandweit einmalige Studie zur Versorgung der Patienten mit Blutkonserven. Ärzteblatt Mecklenburg-Vorpommern 2017;27.
  • Schönborn L et al. Longitudinal Changes in the Blood Supply and Demand in North-East-Germany 2005-2015. Transfus Med Hemother. 2017;44(4):224-31.
  • Greinacher A et al. A population-based longitudinal study on the implication of demographic changes on blood donation and transfusion demand. Blood Adv. 2017;1(14)