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Education and Research Experience
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since 08/2005 |
Research associate in the Junior Research Group Bioinformatics / Toponomics at the Competence Center for Functional Genomics, Ernst Moritz Arndt University, Greifswald |
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05/2001 – 07/2005 |
Research associate at the Institute of Biochemistry - RWTH-Aachen, PhD-thesis entitled: ”Analysis of protein interaction within the Interleukin-6 signal transduction pathway in single cells, mark: summa cum laude |
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04/2001 |
Diploma, mark: ’mit Auszeichnung bestanden’ |
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06/2000 – 04/2001 |
Diploma thesis at the Institute of Biochemistry - RWTH-Aachen, title: "The signal transducer gp130: mechanism of the cytokine-induced receptor activation" |
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07/1999 – 12/1999 |
Student assistant at the Institute of Biochemistry - RWTH-Aachen |
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10/1998 – 02/1999 |
Internship at the Institute of Biochemistry - RWTH-Aachen |
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10/1995 – 04/2001 |
Studies in biology at the Rheinisch-Westfälische Technische Hochschule Aachen (RWTH Aachen) |
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09/1994 – 10/1995 |
Civilian service at the Diakonisches- Werk Aachen |
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06/1994 |
Abitur |
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12/1991 – 06/1994 |
Gymnasium Herzogenrath |
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08/1990 – 12/1991 |
Pascal-Gymnasium in Grevenbroich |
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11/1989 – 06/1990 |
Hölty-Gymnasium in Celle |
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09/1987 – 11/1989 |
Member of the students society of physics at the Humboldt-University, Berlin |
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09/1981 – 11/1989 |
Allgemeinbildende Oberschule in Berlin |
List of publications
Giese, B., Dittmann, S., Paprotka, K., Levin, K., Weltrowski, A., Biehler, D., Lam, T. T., Sinha, B. and Fraunholz, M. J. (2009) Staphylococcal alpha-toxin is not sufficient to mediate escape from phagolysosomes in upper-airway epithelial cells, Infect Immun 77, 3611-3625.
Roderfeld, M., Graf, J., Giese, B., Salguero-Palacios, R., Tschuschner, A., Müller-Newen, G. and Roeb, E. (2007) Latent MMP-9 is bound to TIMP-1 before secretion, Biol Chem 388, 1227–1234.
Giese, B., Roderburg, C., Sommerauer, M., Wortmann, S. B., Metz, S., Heinrich, P. C. and Muller-Newen, G. (2005) Dimerization of the cytokine receptors gp130 and LIFR analysed in single cells, J Cell Sci 118, 5129-5140.
Kruger, T., Benke, D., Eitner, F., Lang, A., Wirtz, M., Hamilton-Williams, E. E., Engel, D., Giese, B., Müller-Newen, G., Floege, J. and Kurts, C. (2004) Identification and functional characterization of dendritic cells in the healthy murine kidney and in experimental glomerulonephritis, J Am Soc Nephrol 15, 613-21.
Herrmann, A., Sommer, U., Pranada, A. L., Giese, B., Kuster, A., Haan, S., Becker, W., Heinrich, P. C. and Müller-Newen, G. (2004) STAT3 is enriched in nuclear bodies, J Cell Sci 117, 339-49.
Hebeisen, S., Biela, A., Giese, B., Müller-Newen, G., Hidalgo, P. and Fahlke, C. (2004) The role of the carboxyl terminus in ClC chloride channel function, J Biol Chem 279, 13140-7.
Behrmann, I., Smyczek, T., Heinrich, P. C., Schmitz-Van de Leur, H., Komyod, W., Giese, B., Müller-Newen, G., Haan, S. and Haan, C. (2004) Janus kinase (Jak) subcellular localization revisited: the exclusive membrane localization of endogenous Janus kinase 1 by cytokine receptor interaction uncovers the Jak-receptor complex to be equivalent to a receptor tyrosine kinase, J Biol Chem 279, 35486-93.
Haug, K., Warnstedt, M., Alekov, A. K., Sander, T., Ramirez, A., Poser, B., Maljevic, S., Hebeisen, S., Kubisch, C., Rebstock, J., Horvath, S., Hallmann, K., Dullinger, J. S., Rau, B., Haverkamp, F., Beyenburg, S., Schulz, H., Janz, D., Giese, B., Müller-Newen, G., Propping, P., Elger, C. E., Fahlke, C., Lerche, H. and Heils, A. (2003) Mutations in CLCN2 encoding a voltage-gated chloride channel are associated with idiopathic generalized epilepsies, Nat Genet 33, 527-32.
Giese, B., Au-Yeung, C. K., Herrmann, A., Diefenbach, S., Haan, C., Kuster, A., Wortmann, S. B., Roderburg, C., Heinrich, P. C., Behrmann, I. and Müller-Newen, G. (2003) Long term association of the cytokine receptor gp130 and the Janus kinase Jak1 revealed by FRAP analysis, J Biol Chem 278, 39205-13.
Pflanz, S., Kernebeck, T., Giese, B., Herrmann, A., Pachta-Nick, M., Stahl, J., Wollmer, A., Heinrich, P. C., Müller-Newen, G. and Grotzinger, J. (2001) Signal transducer gp130: biochemical characterization of the three membrane-proximal extracellular domains and evaluation of their oligomerization potential, Biochem J 356, 605-12.
